bandit king of lunch and string

hey jesse i saw this post and thought of you
https://aethersea.tumblr.com/post/185892301240/

 

Not happy cat smell.

 

hey jesse hey jesse could you tell me what a happy cat smells like

if it's a describable smell anyway i know some are kind of weird and wordless

OuO

 

dear sir, thank u for your recommendation of just get many insulated water cups and profit. it is already proving useful for adhd in sight in mind proof of drinkage.

 

i know for my grandmother it was mostly that, once she'd become dependent, the withdrawal affects of trying to go off the opioids felt worse than any of the nastiness of being on the opioids

also, the degree to which opioids make you miserable is something-something genetics - people in my family generally don't tolerate (the side effects of) opioids very well, anyway, so we usually avoid them like the plague. but for other people, whatever makes the opioids feel nasty just... doesn't trigger? (some of this is epigenetic heritability, like with risk factors if you were exposed as a fetus - but the data concludes either you tolerate opioids better or worse, so idk on that) so it probably feels less like a cactus

 

At least from my experience, different opiates can be pretty different on the side-effect front, too. Codeine was basically worse than the post-surgery pain they gave it to me for and barely even helped, but when I got morphine'd in the ER I just... felt better. I was a little bit fuzzy and loopy, but nothing like the misery that was codeine.

 

That makes sense! i was put on hydrocodone when I was recovering from a surgery, and it 1) didn't actually do anything about my pain and 2) made me so horribly that dizzy & nauseated that I just didn't take it once I was out of the hospital and healed without painkillers because that way at least I was only in pain.

Obviously people get addicted to the stuff anyway, though, so it must do *something* for those people in order for that to even happen. The same medication can hit different people so differently, it's a wonder we ever figured any out to begin with :T

 

One manifestation of addiction (which I think is called "physiological addiction?") is dependence (severe withdrawal symptoms if drug effect reduces) and tolerance (drug effect automatically reducing unless dose increase) combining into a destructive spiral where the addict seeks more and more of the drug until they logistically can't obtain enough to stave off withdrawal and they spin out.

Assuming someone is on a drug that induces (physiological) dependence, they don't need to like it to get physiologically addicted; they just need to be more scared of withdrawal than of continuing to use the substance against medical advice.

 

Sorry to butt in, but one of my professors explained that basically codeine gets metabolized into morphine, and while most of the population metabolizes about 40-50% of it into morphine, some people are under-metabolizers and others are over-metabolizers, so using codeine is a guessing game of genetic information and that is why codeine is bad and you should not prescribe it.

Black Phoenix Alchemy Lab and other similar indie perfumers probably stock something close to some of those.