Speaking of cephalopods, I read a YA book years and years ago with basically giant cuttlefish aliens that were doing... something with Earth. I don't remember many details but that was an instance of an uplifted cephalopod. Sadly no octopus hackers though.
Two words. Uplifited. Lobsters. (Technically not so much "uplifted" as "had their brainstates scanned and digitized, then were let loose on the internet" but still.)
The weirdest I've ever seen was an uplifted coral reef. Because Corey Doctorow. (in his short story I, Row-Boat, which is lovely.)
This is very quickly going Greg Bear's Blood Music. Uplift ALL of the things, then ascend to a higher plane of existence!
Does "Pounded in the Butt by My Own Butt" count? Technically one of the characters is an uplifted butt so...
Hilariously, something sort of like this happens in Phase. Not, like, uplifed coffee grounds or whatever, but the precursor species on Fenn's planet was pretty uplift happy before they decided that a Dyson Swarm seemed like a good idea and fucked off to the realm of the digital. Hey, I had to have *some* explanation for how like six different sentient species could exist on a planet with a tech level slightly above "iron age".
Six different sapient species might be A Thing without uplift on a thicker-aired planet with smaller continents-sophonts would take longer to run into each other and get in the way of developing sophonts, and the thicker air would encourage larger fliers. Flying animals tend to be much smarter than other animals with brains their size-corvids and parrots are at least as smart as chimps, and Alex the genius parrot was arguably sapient. (He asked an unprompted, existential question-"what colour?" about himself.) Anyway-uplifted otters?
Okay, if any of you are familiar with K-PAX? Prot claims that the K-PAXians evolved from worms. Also: Fuck yeah Alex the parrot!
Han Solo fought a giant otter but I'm not sure if it was super smart saoient space ottee or just an otter thst was big that peoplw put jewelry on. I will jave to look thst up.
Ok one of the otters were sapients. The others were just giant flying otters. EU also had an uplifted spider thing. Though he was more like...a bunch of little computers thst joined together to create a space spider information broker that gave boba jobs.